Antimalarial activity of croton macrostachyus stem bark. Fisseha itanna nutrient composition and shortterm release from croton macrostachyus del. Evaluation of antiulcer activity of 80% methanol extract and. In kenya, leaves and roots from croton macrostachyus are used as a traditional medicine for infectious diseases such as typhoid and measles, but reports on possible antimicrobial activity of stem bark do not exist. Download limit exceeded you have exceeded your daily download allowance.
Evaluation of the antidiarrheal activity of the leaf extract. This study aimed to investigate the in vivo antiplasmodial activity of 80% methanol extract of the fruit and the root of croton macrostachyus h. Among these, croton macrostachyus is one such plant claimed to have an antidiarrheal activity in ethiopian folklore medicine. Treecrop based farming, gemechis, croton macrostachyus, hararghe, soil. The methanol and chloroform plant extracts of withania somnifera, azadirachta indica, croton macrostachyus and leonotis nepetifolia showed significant antibacterial activity against 160 clinical isolates of salmonella and shigella sp collected from pediatric division of the adama referral government hospital, adama, ethiopia. Enjoy unrestricted access to all content and features, including.
Croton macrostachyus, one of the croton species found in ethiopia, is used traditionally for treatment of a number of health ailments including diabetes, malaria, stomachache, ascariasis, abdominal pain, gonorrhea, wounds, ringworm infestation and hemorrhoids. Euphorbiaceae is a tall tree widely distributed in mountainous forests and savannah of the tropical regions. Croton is an extensive flowering plant genus in the spurge family, euphorbiaceae. Those 31 medicinal plant species were treated around 32 different human ailments. Croton macrostachyus is a multipurpose, mediumsized tree of pantropic occurrence. Croton macrostachyus hochst pipe cleaner ex and galinier, is a plant used in african folk medicine to treat different ailments, including pain and inflammation 7, 8. The crude extract was obtained by cold maceration in 80% methanol and fractionated with chloroform, ethyl acetate, and distilled water. Since it showed cytotoxicity on hct116 human colon cancer cell lines, further separation was performed, and two single diterpene compounds were obtained. Agar dilution method was used to evaluate in vitro anti n. Ethnopharmacological uses, phytochemistry, and pharmacological. Antifungals and acetylcholinesterase inhibitors from the stem bark of croton heliotropiifolius. Antimicrobial activity of croton macrostachyus stem bark extracts against several human pathogenic bacteria. Croton macrostachyus in the germplasm resources information network grin, u. The database and code is licensed under a creative commons attributionnoncommercialsharealike 3.
The abundance of the reported medicinal plant species also showed variation with their added values. A rodent malaria parasite, plasmodium berghei, was used to inoculate healthy male swiss albino mice of age 68 weeks and weight 2327 g. The results can also be downloaded as a csv file unicode utf8 encoding see status, confidence level, source for definitions. Bridelia micrantha and croton macrostachyus are medicinal plants used empirically in traditional medicine to treat epilepsy. In kenya, leaves and roots from croton macrostachyus are used as a traditional medicine for infectious diseases such as typhoid and measles. The methanol and aqueous extracts of acokanthera schimperi showed the highest yield with 37. Download pdf invitro and invivo antibacterial activities of croton macrostachyus methanol extract against e. Cardioprotective effect of croton macrostachyus stem bark. Croton macrostachyus in the present study the in vivo assays showed that the studied extracts of c. Medicinal although somewhat toxic, broadleaved croton is widely used in traditional african medicine. Traditional healers in ethiopia use a wide range of medicinal plants with antidiarrheal properties. Usda, ars, germplasm resources information network. In vivo antimalarial activity of the crude root and fruit extracts of croton macrostachyus.
Most parts of the plant are employed in the treatment of various conditions, but it is especially valued for ridding the body of parasites and toxins, and for dealing with skin problems. Phytochemical investigation of seeds of achyranthes aspera linn. In the in vivo acute toxicity studies of the plant extracts, there were no gross physical and behavioral changes. Croton macrostachyus is traditionally used to treat peptic ulcer in ethiopia. The mice in the three treatment groups received extract from the acokanthera schimperi and croton macrostachyus 0. An alternative source for discovering such drugs is natural products. Sep 29, 2016 traditional healers in ethiopia use a wide range of medicinal plants with antidiarrheal properties. Description of the study area oda bultum district is found in west hararghe zone, oromia national regional state, ethiopia. In the present prophylaxis assay the impact macrostachyud the most active ethyl acetate extract containing lupeol is linear and thus may reflect the indirect effect of lupeol on the erythrocyte membrane. Croton macrostachyus has a long taproot and numerous sideroots, which makes it adapted to dry climates. Even as a large shrub or small tree the plant can enter reproductive state. Croton species croton macrostachyus name synonyms croton macrostachyus hochst. Croton macrostachyus can be lopped, pollarded or coppiced.
Trpv1 channel inhibition contributes to the antinociceptive. To evaluate the antioxidant and cardioprotective activities of stem bark extract and solvent fractions of croton macrostachyus on cyclophosphamideinduced cardiotoxicity in rats. A decoction of the leafy twigs mixed with justicia schimperiana. Biological evaluation of the diterpenes from croton. Croton macrostachyus is widely used as herbal medicine by the indigenous people of tropical africa.
Croton megalocarpus, is a plant species in the family euphorbiaceae. Croton macrostachyus dataset ncbi taxonomy rank species classification kingdom. The main constituents of the oil were benzyl benzoate 51. Pdf nutrient composition and shortterm release from croton. In vivo mice model maximal electroshock, strychnine, pentylenetetrazol, picrotoxin, isonicotinic hydrazide acidinduced convulsions were used to evaluate the anticonvulsant activities of those plants. Croton macrostachyus images useful tropical plants. B, abstract the seeds of achyranthes aspera linn is a common plant and is having wide variety of applications like. Biological evaluation of the diterpenes from croton macrostachyus. Research article antimalarial activity of croton macrostachyus stem. The pdf file you selected should load here if your web browser has a pdf reader plugin installed for example, a recent version of adobe acrobat reader if you would like more information about how to print, save, and work with pdfs, highwire press provides a helpful frequently asked questions about pdfs. Because the species has numerous useful qualities e.
This study demonstrated that croton macrostachyus tree that was retained on crop fields improve soil properties under its canopy very considerably and this makes its integration into the farming system worthy and promising in the area. Thirty healers were selected to collect data on management of. Department of agriculture agricultural research service. Crotomacrine, a new clerodane diterpene from the fruits of. The oil was tested for its in vitro antileishmanial activity on two leishmania strains, and its toxicity on the human monocytic leukemia thp1 cell line and erythrocytes from sheep blood. In a forest, for example at kakamega, croton trees exceeding 25 m can be found.
This study aimed to evaluate the antiulcer activity of c. Croton macrostachyus a and eucalyptus b trees along maize farm borders, and the under growth density within a coffee garden c and a eucalyptusstand d. Germination responses of croton macrostachyus euphorbiaceae to various physicochemical pretreatment conditions article pdf available in south african journal of botany 87. Triterpenoids and phenolic compounds from croton macrostachyus. Constituents, antileishmanial activity and toxicity. However, no further scientific investigations have been carried out to. Antifungals and acetylcholinesterase inhibitors from the stem. Evaluation of the antidiarrheal activity of the leaf extract of croton. Larvicidal activity of cymbopogon citratus dc stapf. Euphorbiaceae stem bark extracts from kenyan folkloric medicine. Abstract an experimental trial was conducted to investigate the invitro and invivo antibacterial activity of croton macrostachyus leaf extracts against escherichia coli and staphylococcus aureus. Croton macrostachyus has compounds isolated from its root.
In vivo antimalarial activity of the crude root and fruit. Family euphorbiaceae vernacular names woodland croton, forest fever tree, broadleaved croton en. In the present study, phytochemical screening of ethanol extract from leaves of c. Click below on a thumbnail map or name for species profiles. Decoctions of bridelia micrantha and croton macrostachyus may.
An ethnobotanical study of medicinal plants in wonago. This study also documented that drought, overgrazing and firewood collection are major. Access is allocated within two business days of purchase and lasts one year. Creative commons attributionnoncommercialsharealike 3. Indeed, previous studies have shown that aqueous and organic extracts from the stem bark of c. Download fulltext pdf download fulltext pdf medicinal value of croton macrostachyus and solanum incanum against causative agent of foodborne diseases article pdf available november 2019. In vitro antineisseria gonorrhoeae activity of albizia.
A preliminary checklist of the vascular plants of mozambique. To clarify whether the seeds of croton macrostachyus can induce apoptosis, its methanolic extract was first subjected to a clonogenic survival assay, which measures longterm cytotoxic effects. The issue of resistance in malarial infection makes development of novel drugs a necessity. The record derives from wcsp data supplied on 20120323 which reports it as an accepted name record 50457 with original publication details. The plants of this genus were described and introduced to europeans by georg eberhard rumphius. Medicinal plants are the integral part of the variety of cultures in ethiopia and have been used over many centuries. The rodent malaria parasite plasmodium berghei was used to inoculate healthy 8weekold male swiss albino mice weighing 2327 g. However, no further scientific investigations have been carried out to substantiate the claim. Status of selected soil properties under croton macrostachyus. Journal of medicinal plants research isolation and. Ethnopharmacologic survey of medicinal plants used to.
Useful tropical plants database 2014 by ken fern, web interface by ajna fern with help from richard morris. Pdf medicinal value of croton macrostachyus and solanum. This study therefore aimed at investigating the in vivo antiplasmodial activity of 80% methanol extract and solvent fractions of the leaves of croton macrostachyus h. Aug 26, 2014 treatment commenced 3 hours after infection on day 0 and then continued daily for four days i. Euphorbiaceae which is commonly known as broadleaved croton english, bisana amharic, tambuk and tambush tigrigna, and abnga in berta ethnic group, 14 is endowed with a number of ethnomedicinal uses in ethiopia 12, 15, 16. The pdf file you selected should load here if your web browser has a pdf reader plugin installed for example, a recent version of adobe acrobat reader if you would like more information about how to print, save, and work with pdfs, highwire press provides a helpful frequently asked questions about pdfs alternatively, you can download the pdf file directly to your computer, from where it. Croton zambesicus exhibited moderate larvicidal activity with lc 50 value of 155. Croton macrostachyus and leonotis nepetifolia showed significant antibacterial activity against 160 clinical isolates of salmonella and shigella sp collected from pediatric division of the adama referral government hospital, adama, ethiopia. Ecohydrological impacts of eucalyptus in the semi humid ethiopian highlands. Experimental evaluation of wound healing activity of croton. Assessment of indigenous knowledge of medicinal plants in. Albert et al37 reported analgesic and antiinflammatory properties of the aqueous and methylene chloridemethanol extracts of the stem bark of croton macrostachyus. Dinesh reddy somagari, karisetty basappa, srikanth rolla, pothuganti jithendar, rajashekar. Croton macrostachyus leaves are used for treatment of wounds by traditional healers in.
Croton macrostachyus is one of the plant species used for the smoking. In this study, the antibacterial and antifungal effects of methanol, ethyl acetate and butanol extracts, and purified lupeol of c. This paper forms part of a special issue of phytochemistry letters dedicated to the memory of andrew marston 195320, outstanding phytochemist who is much missed by his friends. Protabase record display croton macrostachyus hochst. Pdf antimicrobial activity of croton macrostachyus stem.
Infectious diseases archives pagina 11 di 11 european. Croton macrostachyus, excision, incision, in vivo, wound healing. The common names for this genus are rushfoil and croton, but the latter also refers to codiaeum variegatum. Ecohydrological impacts of eucalyptus in the semi humid. Ethnobotanical profile of croton macrostachyus euphorbiaceae in. Please note that this is a trial program and may end. Croton macrostachyus has potential as a possible source of a wide range of pharmaceutical products for the treatment of a wide range of both human and animal diseases and ailments. Surface 015 cm and subsurface 3045 cm soil samples from under canopy, edge of canopy and away from canopy of isolated cordia africana lam. Hence, the aim of this study is to document the medicinal plants in the natural vegetation and home gardens in wonago woreda, gedeo zone, southern nations, nationalities and peoples regional state snnpr. Euphorbiaceae is used in ethiopian folklore medicine for the treatment of malaria and found to possess antimalarial activity in vitro. Euphorbiaceae is a multipurpose, deciduous, and medium sized tree of pantropic occurrence. The plants database includes the following 50 species of croton. In vivo antimalarial activity of the crude leaf extract and. A preliminary phytochemical investigation of croton.
Issn phytochemical investigation of seeds of achyranthes. Constituents, antileishmanial activity and toxicity profile. The chemical composition of the volatile oil from berries of croton macrostachyus hochst. Cordiaafricana and croton macrostachyus trees scattered in farmland on selected soil properties, microclimatic variables and maize grain yield.
Previous studies showed that the crude extract is endowed with the claimed property. Ethnopharmacologic survey of medicinal plants used to treat. The present study was undertaken to further the claim by screening different. In vivo antimalarial activity of the crude leaf extract. Evaluation of antimalarial activity of leaves of acokanthera. Germination responses of croton macrostachyus euphorbiaceae.
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